USProbiotics.org

Clinical Study Highlight

An investigation of recent clinical studies with a summary and comments
by Mary Ellen Sanders, Ph.D.

Featured Study – April 2008
Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial - BMJ. 2007 Jul 14;335(7610):80.

Featured Study – March 2007
Augmentation of antimicrobial metronidazole therapy of bacterial vaginosis with oral probiotic Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14: randomized, double-blind, placebo controlled trial – Microbes and Infection. 8: 1450-1454.

Featured Study – May 2006
Increasing work-place healthiness with the probiotic Lactobacillus reuteri: a randomised, double-blind placebo-controlled study – Environ Health. 4:25.

Featured Study – November 2005
Effect of lactobacillus in preventing post-antibiotic vulvovaginal candidiasis: a randomised controlled trial – BMJ. 2004 Sep 4;329(7465):548

Featured Study – June 2005
Lactobacillus and Bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles – Gastroenterology 128(3): 541-51

Featured Study – January 2005
Effect of a probiotic infant formula on infections in child care centers: comparison of two probiotic agents – Pediatrics 115(1):5-9.

Featured Study – October 2004
Randomised clinical trial of synbiotic therapy in elective surgical patients – Gut 53(2):241-5.

Featured Study – February 2004
Ingested probiotics reduce nasal colonization with pathogenic bacteria (Staphylococcus aureus, Streptococcus pneumoniae, and b-hemolytic streptococci) - Am J. Clin. Nutr. 77:517-520

Featured Study - November 2003
Prophylaxis of pouchitis onset with probiotic therapy: a double-blind, placebo-controlled trial. - Gastroenterology 2003 May; 124:1202-9

Featured Study - June 2003
Effect of probiotic Lactobacillus strains in children with atopic dermatitis. - J Allergy Clin Immunol 2003 Feb;111(2):389-95

Featured Study - April 2003
Use of fermented foods to combat stunting and failure to thrive. - Nutrition 18:393-396

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Probiotics, probiotic research and probiotic foods are fast growing topics as consumer awareness continues to increase. The USprobiotics.org site is a comprehensive, up-to-date resource on probiotic reseach and development and the consumer health benefits of probiotics in the United States as well as a reference for global probiotic activities. This site will give consumers, healthcare professionals and industry professionals a good background on the world of probiotics – what they are, what we know about them, and what to consider for commercial and personal use. Webcast Probiotics: Applications in Gastrointestinal Health & Disease Presented in conjunction with the American College of Gastroenterology’s 72nd Annual Scientific Meeting held October 16, 2007 Program Proceedings (PDF) Program made possible through an unrestricted educational grant provided by The Dannon Company, Inc. and Yakult Honsha Co., Ltd.	Clinical Study Highlight An investigation of recent clinical studies with a summary and comments by Mary Ellen Sanders, Ph.D. Featured Study – April 2008 Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial - BMJ. 2007 Jul 14;335(7610):80. Featured Study – March 2007 Augmentation of antimicrobial metronidazole therapy of bacterial vaginosis with oral probiotic Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14: randomized, double-blind, placebo controlled trial – Microbes and Infection. 8: 1450-1454. Featured Study – May 2006 Increasing work-place healthiness with the probiotic Lactobacillus reuteri: a randomised, double-blind placebo-controlled study – Environ Health. 4:25. Featured Study – November 2005 Effect of lactobacillus in preventing post-antibiotic vulvovaginal candidiasis: a randomised controlled trial – BMJ. 2004 Sep 4;329(7465):548 Featured Study – June 2005 Lactobacillus and Bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles – Gastroenterology 128(3): 541-51 Featured Study – January 2005 Effect of a probiotic infant formula on infections in child care centers: comparison of two probiotic agents – Pediatrics 115(1):5-9. Featured Study – October 2004 Randomised clinical trial of synbiotic therapy in elective surgical patients – Gut 53(2):241-5. Featured Study – February 2004 Ingested probiotics reduce nasal colonization with pathogenic bacteria (Staphylococcus aureus, Streptococcus pneumoniae, and b-hemolytic streptococci) - Am J. Clin. Nutr. 77:517-520 Featured Study - November 2003 Prophylaxis of pouchitis onset with probiotic therapy: a double-blind, placebo-controlled trial. - Gastroenterology 2003 May; 124:1202-9 Featured Study - June 2003 Effect of probiotic Lactobacillus strains in children with atopic dermatitis. - J Allergy Clin Immunol 2003 Feb;111(2):389-95 Featured Study - April 2003 Use of fermented foods to combat stunting and failure to thrive. - Nutrition 18:393-396